The Palladam to Kayalpattinam bus route covers approximately 340 kms and takes about 6 hrs 32 mins. A total of 12 direct buses operated by 9 bus operators run on this route. The first bus departs at 01:30, and the last bus leaves at 23:45.
Major boarding points in Palladam include Avinashi New Bus Stand, Avinashipalayam, Palladam, while common drop locations in Kayalpattinam are A to Z travels, Adaikalapuram, Kayalpattinam, Kayalpattinam ByPass, Kumaresan Travels.
RTC and private operators such as Jayam travels offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 399 - INR 2090.00 depending on the bus type and features.



