The Mysore to Madurai bus route covers approximately 395 kms and takes about 12 hrs 13 mins. A total of 5 direct buses operated by 2 bus operators run on this route. The first bus departs at 17:15, and the last bus leaves at 19:30.
Major boarding points in Mysore include Colombia Asia Hospital, Infosys Gate, JSS Medical College, KSRTC Bus Stand, while common drop locations in Madurai are Fathima College, Govt Hospital, K K Nagar, Kalavasal, Kochadai, Mattuthavani, Others, Periyar Bus Stand, Samyanallur Bypass.
RTC and private operators such as KSRTC (Karnataka) offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 828 - INR 2351.00 depending on the bus type and features.



