The Villupuram to Sayalkudi bus route covers approximately 401 kms and takes about 7 hrs 23 mins. A total of 15 direct buses operated by 6 bus operators run on this route. The first bus departs at 00:15, and the last bus leaves at 23:59.
Major boarding points in Villupuram include Villupuram Bypass, while common drop locations in Sayalkudi are Shanthi Petrol Bunk.
RTC and private operators such as (SBLT) Shri Bhagiyalakshimi Travels (MAARA), Sri Krishna Travels offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 399 - INR 2000.00 depending on the bus type and features.



