The Tiruchirapalli to Periyakulam bus route covers approximately 166 kms and takes about 2 hrs 41 mins. A total of 31 direct buses operated by 16 bus operators run on this route. The first bus departs at 02:00, and the last bus leaves at 21:15.
Major boarding points in Tiruchirapalli include Central Bus Stand, Kattur Bus Stop, Mannarpuram, Mathur Roundana, No 1 Toll Gate, Palpannai, Perambalur, Railway Junction, Samayapuram, Srm Medical College, while common drop locations in Periyakulam are Lakshmipuram, Periyakulam Road.
RTC and private operators such as Thirumal Alaghu Travels (TAT), Sri Krishna Travels offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 348 - INR 1599.00 depending on the bus type and features.



