The Mettupalayam to Tirunelveli bus route covers approximately 369 kms and takes about 8 hrs 39 mins. A total of 9 direct buses operated by 7 bus operators run on this route. The first bus departs at 20:00, and the last bus leaves at 22:31.
Major boarding points in Mettupalayam include Kavundampalayam, Narasimhanaickenpalayam, Periyanyakanpalayam, Thudiyalur, while common drop locations in Tirunelveli are Kayathar, Others, Passport Seva Kendra, Sankarnagar, Tirunelveli bypass, Udayarpatti, Vannarpettai.
RTC and private operators such as Air Indiaa Travels, Jai Vishnu Travels, GNK Travels offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 890 - INR 3499.00 depending on the bus type and features.



