The Chennai to Papanasam(Tirunelveli) bus route covers approximately 638 kms and takes about 12 hrs 52 mins. A total of 8 direct buses operated by 6 bus operators run on this route. The first bus departs at 18:00, and the last bus leaves at 20:00.
Major boarding points in Chennai include Ambattur, Anna Nagar, Ashok Pillar, Chengalpattu, Chrompet, Ekkattuthangal, Guduvancheri, Guindy, Injambakkam, Kanchipuram, while common drop locations in Papanasam(Tirunelveli) are Papanasam.
RTC and private operators such as Sri Selvam Travels (PSP), (SBLT) Shri Bhagiyalakshimi Travels (MAARA), National Travels CHN offer Volvo, AC, and non-AC seater and sleeper buses. Ticket prices on redBus range from INR 500 - INR 2999.00 depending on the bus type and features.



